Migraine Guidelines: NEW ORLEANS — Seven different drugs are proven to be effective for preventing episodic migraine attacks and another half-dozen are probably helpful, according to new guidelines released here by the American Academy of Neurology (AAN).
An evidence review by the AAN and the American Headache Society also identified several over-the-counter (OTC) products, including herbal supplements, with either proven or probable efficacy.
The announcement accompanied publication of two practice guidelines on prevention of episodic migraine — one for prescription products and another for nonsteroid anti-inflammatory drugs and “complementary” therapies — in the April 24 issue ofNeurology.
Prescription drugs listed as having proven effectiveness against migraine, defined as a significant benefit in at least two high-quality randomized trials, included one triptan agent, three beta-blockers, and three anti-epileptic drugs.
Only one OTC product has established efficacy, according to the guideline: the herbal supplement known as Petasites or butterbur.